AirOrSeaTravel is an independent guide. Bookings on this page are completed on the provider’s own website. How we are funded.

AirOrSeaTravel — find your way there
Santa Fe · Argentina

Car hire and driving in Santa Fe

Driving distances to the cities around, the rules that change at the border, and where to compare rental prices.

OverviewFlightsHotelsTrainsBusesCar rentalTours

In Argentina traffic drives on the right. Picking up at SFN means 12 km (7 mi) into the centre before the trip starts. The emergency number is http://www.wikidata.org/entity/Q25648793 / http://www.wikidata.org/entity/Q25648794 / http://www.wikidata.org/entity/Q4547615.

Drives from Santa Fe

Car rental from Santa Fe: distances and estimated journey times
RouteCountryDistanceEstimated time
Santa Fe to RosarioArgentina144 km (90 mi)about 2 h 12 min
Santa Fe to San Nicolás de los ArroyosArgentina193 km (120 mi)about 2 h 57 min
Santa Fe to ConcordiaArgentina257 km (160 mi)about 3 h 55 min
Santa Fe to SaltoUruguay262 km (163 mi)about 4 h
Santa Fe to CórdobaArgentina331 km (206 mi)about 5 h 3 min
Santa Fe to José C. PazArgentina366 km (228 mi)about 5 h 35 min
Santa Fe to San MiguelArgentina372 km (231 mi)about 5 h 40 min
Santa Fe to MorenoArgentina377 km (234 mi)about 5 h 45 min
Santa Fe to Río CuartoArgentina380 km (236 mi)about 5 h 47 min
Santa Fe to MerloArgentina383 km (238 mi)about 5 h 50 min
Santa Fe to CastelarArgentina385 km (239 mi)about 5 h 53 min
Santa Fe to San JustoArgentina392 km (243 mi)about 5 h 59 min
Santa Fe to São PauloBrazil1,651 km (1,026 mi)about 25 h 11 min
Santa Fe to SantiagoChile953 km (592 mi)about 14 h 32 min
Santa Fe to Buenos AiresArgentina395 km (245 mi)about 6 h 1 min
Santa Fe to CuritibaBrazil1,313 km (816 mi)about 20 h 1 min
Santa Fe to Santa Cruz de la SierraBolivia1,561 km (970 mi)about 23 h 49 min
Santa Fe to Porto AlegreBrazil922 km (573 mi)about 14 h 4 min
Santa Fe to AsunciónParaguay768 km (477 mi)about 11 h 43 min
Santa Fe to GuarulhosBrazil1,665 km (1,035 mi)about 25 h 24 min

Distances are straight-line; road and rail routes run about 15–25% longer. Times are estimates from distance and typical speeds, not timetables.

Where to compare car hire

ExpediaCar hire from the major suppliers, and the one to look at if the flight or hotel is already booked there. Part of Expedia Group.Check car hire on Expedia (opens www.expedia.com in a new tab)
DiscoverCarsCompares local and international suppliers. Read the counter reviews before you pick.Check rental cars on DiscoverCars (opens www.discovercars.com in a new tab)
Rentalcars.comBooking.com's car arm, with wide airport coverage worldwide.Compare suppliers on Rentalcars.com (opens www.rentalcars.com in a new tab)
Every link above leaves this site.

We take no bookings for these providers and hold no reservation with them. The provider you choose handles payment, confirmation, changes and refunds. How that works.

Common questions

Which side of the road do they drive on in Santa Fe?

The right, as everywhere in Argentina.

How are the journey times on this page worked out?

From straight-line distance and typical speeds for each mode, so they are estimates for planning, not timetables. Road and rail routes run 15–25% longer than the straight line.

Where these facts come from

  • GeoNames (CC BY 4.0): population, elevation, time zone, postal codes
  • Wikidata (CC0): area, sister cities, visitor numbers, heritage listings, stations and ports
  • OurAirports (public domain): airports, runways
  • Natural Earth (public domain): map outlines

Data compiled 14 September 2026. Hotel and hostel figures are from our booking partner’s catalogue on that date. Journey times on this page are estimates from distance, not timetables; check the operator before you rely on one.