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Indianapolis → St. Louis

Driving from Indianapolis to St. Louis

St. Louis lies 370 km (230 mi) west of Indianapolis, -1 h on the clock. What the numbers say about getting there.

Driving takes about 5 h 1 min without stops, over roughly 452 km (281 mi) of road; add breaks, fuel and any border.

IndianapolisSt. Louis

Open St. Louis in Google Maps

The two ends, side by side
IndianapolisSt. Louis
CountryUnited StatesUnited States
Population887,642279,695
Elevation248 m (814 ft)149 m (489 ft)
Time nowUTC-4 (America/Indiana/Indianapolis)UTC-5 (America/Chicago)

Clocks in St. Louis are 1 h behind Indianapolis right now, so a 5 h 1 min journey lands only 4 h 1 min later by the destination clock.

Where to book car hire from Indianapolis to St. Louis

ExpediaCar hire from the major suppliers, and the one to look at if the flight or hotel is already booked there. Part of Expedia Group.Check car hire on Expedia (opens www.expedia.com in a new tab)
DiscoverCarsCompares local and international suppliers. Read the counter reviews before you pick.Check rental cars on DiscoverCars (opens www.discovercars.com in a new tab)
Rentalcars.comBooking.com's car arm, with wide airport coverage worldwide.Compare suppliers on Rentalcars.com (opens www.rentalcars.com in a new tab)
Every link above leaves this site.

We take no bookings for these providers and hold no reservation with them. The provider you choose handles payment, confirmation, changes and refunds. How that works.

Staying in St. Louis

Live rooms and prices for St. Louis are in the search below.

Book a hotel in St. Louis

Live rooms and prices from our booking partner, booked and paid for here. Free cancellation is marked where it applies.

Common questions

How far is St. Louis from Indianapolis?

370 km (230 mi) in a straight line, west of Indianapolis; by road roughly 452 km (281 mi).

How long does it take to get from Indianapolis to St. Louis by car?

About 5 h 1 min, estimated from distance and typical speeds. Timetables and traffic decide the real figure.

Is there a time difference between Indianapolis and St. Louis?

St. Louis is 1 h behind at the moment (America/Chicago against America/Indiana/Indianapolis).

Where these facts come from

  • GeoNames (CC BY 4.0): population, elevation, time zone, postal codes
  • Wikidata (CC0): area, sister cities, visitor numbers, heritage listings, stations and ports
  • OurAirports (public domain): airports, runways
  • Natural Earth (public domain): map outlines

Data compiled 13 September 2026. Hotel figures are from our booking partner’s catalogue on that date. Journey times on this page are estimates from distance, not timetables; check the operator before you rely on one.